SCHEMBL7203043

SCHEMBL7203043

Cc1ccc(C(=O)O)c(C(=O)O)c1Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.46
HNF4A P41235 1/20 0.46
ALDH1A1 P00352 2/20 0.45
LDHA P00338 3/20 0.43
LDHB P07195 3/20 0.43
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
AKR1C3 P42330 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
PTPN1 P18031 2/20 0.41
NOTUM Q6P988 2/20 0.41
PTPN2 P17706 1/20 0.41
PTPN6 P29350 1/20 0.41
HTT P42858 1/20 0.40
TSHR P16473 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27383635 0.87 ALDH1A1 (0.45) IDH1HNF4AALDH1A1LDHALDHB
SCHEMBL29921822 0.86 HNF4A (0.51) HNF4AALDH1A1LMNAKMT2AMEN1
SCHEMBL7204828 0.85 IDH1 (0.47) IDH1HNF4AALDH1A1LDHALDHB
SCHEMBL17941538 0.83 ALDH1A1 (0.49) IDH1HNF4AALDH1A1LDHALDHB
SCHEMBL1888529 0.81 PTPN1 (0.49) HNF4AALDH1A1LDHALDHBLMNA
SCHEMBL27946071 0.81 LDHA (0.48) IDH1HNF4AALDH1A1LDHALDHB
SCHEMBL29922019 0.80 PTPN1 (0.53) HNF4AALDH1A1LMNAKMT2AMEN1
SCHEMBL3271724 0.79 ALDH1A1 (0.52) IDH1HNF4AALDH1A1LMNAKMT2A
SCHEMBL3000590 0.79 GABRP (0.40) ALDH1A1LDHALDHBKMT2ANOTUM
SCHEMBL7036187 0.79 ALDH1A1 (0.42) IDH1HNF4AALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003078377-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC AND OTHER OXIDATION PRODUCTS BY THE CONTROLLED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed
WO-2003078369-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC ACID AND OTHER OXIDATION PRODUCTS BY THE STAGGERED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed