Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.69 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.69 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.69 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.69 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.64 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204210 | 0.91 | ITGAV (0.74) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6668568 | 0.90 | ITGAV (0.81) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7170078 | 0.89 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7170092 | 0.89 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6671127 | 0.88 | ITGAV (0.73) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7174008 | 0.88 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7174024 | 0.88 | ITGAV (0.72) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL7209958 | 0.88 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6670827 | 0.88 | ITGAV (0.79) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL22223299 | 0.87 | ITGAV (0.71) | ITGAVITGB3ITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171304-A1 | Pyridine-2-yl-aminoalkyl carbonyl glycyl-$g(b)-alanine and derivatives thereof | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171304-A1 | Pyridine-2-yl-aminoalkyl carbonyl glycyl-$g(b)-alanine and derivatives thereof | GLRB, GLRA3, HAO2 | ITGAV 2128/4885ITGB3 501/4885ITGB6 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.