Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19746790 | 0.80 | POLB (0.57) | MEN1KMT2ATDP1BACE1KDM4E | |
| SCHEMBL27271137 | 0.77 | BACE1 (0.52) | MEN1KMT2ATDP1BACE1KDM4E | |
| SCHEMBL24429207 | 0.76 | MEN1 (0.51) | MEN1KMT2ATDP1BACE1KDM4E | |
| SCHEMBL4352870 | 0.74 | KMT2A (0.55) | MEN1KMT2ATDP1TSHRHTT | |
| Iodohippurate SCHEMBL589803 | 0.73 | KMT2A (0.58) | MEN1KMT2ATDP1KDM4ERAB9A | |
| Iodohippurate SCHEMBL29959499 | 0.73 | KMT2A (0.58) | MEN1KMT2ATDP1KDM4ERAB9A | |
| SCHEMBL772204 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2ATDP1KDM4ESIGMAR1 | |
| SCHEMBL13667371 | 0.71 | MEN1 (0.51) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL20963267 | 0.71 | HPGD (0.56) | MEN1KMT2ATDP1KDM4EHTT | |
| Iodohippurate SCHEMBL2142713 | 0.71 | KMT2A (0.56) | MEN1KMT2ATDP1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1092723-A2 | Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |