SCHEMBL7204993

SCHEMBL7204993

CC(=Cc1ccc(-c2cc(C=C(C)C(=O)O)ccc2-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.61
TP53 P04637 1/20 0.49
LTB4R Q15722 1/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
APEX1 P27695 7/20 0.41
TBXAS1 P24557 3/20 0.41
HTT P42858 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
NR4A2 P43354 1/20 0.40
RXRG P48443 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
ESR1 P03372 1/20 0.39
MPL P40238 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7209266 0.97 AKR1C3 (0.59) AKR1C3TP53LTB4RLTB4R2APEX1
SCHEMBL532624 0.85 AKR1C3 (0.77) AKR1C3TP53APEX1TBXAS1HTT
SCHEMBL532625 0.85 AKR1C3 (0.77) AKR1C3TP53APEX1TBXAS1HTT
SCHEMBL4201965 0.83 AKR1C3 (0.54) AKR1C3APEX1MEN1KMT2A
SCHEMBL4201960 0.83 AKR1C3 (0.54) AKR1C3APEX1MEN1KMT2A
Biphenyl SCHEMBL28220466 0.79 AKR1C3 (0.88) AKR1C3TP53APEX1TBXAS1HTT
SCHEMBL17603252 0.79 AKR1C3 (0.62) AKR1C3TP53LTB4RAPEX1TBXAS1
SCHEMBL17603251 0.79 AKR1C3 (0.62) AKR1C3TP53LTB4RAPEX1TBXAS1
SCHEMBL3414243 0.79 AKR1C3 (0.72) AKR1C3TP53APEX1TBXAS1HTT
SCHEMBL2732933 0.79 AKR1C3 (0.72) AKR1C3TP53APEX1TBXAS1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643318-B1 DISPLAY DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORP (JP) 2003-01-02 EP disclosed
US-6261650-B1 Polymer dispersed liquid crystal (PDLC) display element for use in an electronic apparatus SEIKO EPSON CORPORATION (JP) 2001-07-17 US disclosed
US-5993689-A Polymer dispersed liquid crystal (PDLC) display element for use in an electronic apparatus SEIKO EPSON CORPORATION (JP) 1999-11-30 US disclosed
US-5686017-A Polymer dispersed liquid crystal (PDLC) display element for use in an electronic apparatus SEIKO EPSON CORPORATION (JP) 1997-11-11 US disclosed
EP-0643318-A1 DISPLAY DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 1995-03-15 EP disclosed