Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 6/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210690 | 1.00 | KMT2A (0.38) | KMT2AMEN1EPHX2KDM5AKDM4C | |
| SCHEMBL4805159 | 0.85 | LSS (0.48) | LSS | |
| SCHEMBL7209034 | 0.82 | GBA1 (0.53) | KMT2AMEN1LMNA | |
| SCHEMBL7210722 | 0.82 | KMT2A (0.38) | KMT2AMEN1EPHX2KDM5AKDM4C | |
| SCHEMBL7205014 | 0.81 | LSS (0.36) | EPHX2KDM5AKDM4CPHF8S1PR2 | |
| SCHEMBL7210693 | 0.81 | LSS (0.36) | EPHX2KDM5AKDM4CPHF8S1PR2 | |
| SCHEMBL7205012 | 0.81 | LSS (0.36) | EPHX2KDM5AKDM4CPHF8S1PR2 | |
| SCHEMBL7210695 | 0.81 | LSS (0.36) | EPHX2KDM5AKDM4CPHF8S1PR2 | |
| SCHEMBL7204867 | 0.78 | LMNA (0.44) | KMT2AMEN1LMNA | |
| SCHEMBL7205051 | 0.78 | LSS (0.46) | KMT2ALMNACNR2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |