Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205051 | 0.88 | LSS (0.46) | GBA1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7204867 | 0.88 | LMNA (0.44) | GBA1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7207312 | 0.86 | LMNA (0.45) | GBA1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7205007 | 0.82 | KMT2A (0.38) | KMT2ALMNAMEN1 | |
| SCHEMBL7210690 | 0.82 | KMT2A (0.38) | KMT2ALMNAMEN1 | |
| SCHEMBL7209029 | 0.80 | HTR2A (0.48) | KMT2AALDH1A1MEN1 | |
| SCHEMBL7209032 | 0.80 | HTR2A (0.48) | KMT2AALDH1A1MEN1 | |
| SCHEMBL7211489 | 0.80 | NAAA (0.45) | PKM | |
| SCHEMBL5092120 | 0.79 | LSS (0.46) | GBA1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7206982 | 0.79 | HTR2A (0.49) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |