Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207312 | 0.99 | LMNA (0.45) | LMNAALDH1A1KCNH2THRBHPGD | |
| SCHEMBL7209034 | 0.88 | GBA1 (0.53) | LMNAALDH1A1THRBHPGDHTT | |
| SCHEMBL7205051 | 0.85 | LSS (0.46) | LMNAALDH1A1THRBHPGDHTT | |
| SCHEMBL7206188 | 0.84 | ALDH1A1 (0.40) | LMNAALDH1A1KCNH2THRBHPGD | |
| SCHEMBL7204863 | 0.82 | HTR2A (0.47) | ALDH1A1KCNH2CYP19A1KMT2AMAPT | |
| SCHEMBL7204860 | 0.82 | HTR2A (0.47) | ALDH1A1KCNH2CYP19A1KMT2AMAPT | |
| SCHEMBL7207309 | 0.81 | HTR2A (0.47) | ALDH1A1KCNH2CYP19A1KMT2AMAPT | |
| SCHEMBL7209122 | 0.81 | HTR2A (0.47) | ALDH1A1KCNH2CYP19A1KMT2AMAPT | |
| SCHEMBL7210690 | 0.78 | KMT2A (0.38) | LMNAKMT2AMEN1 | |
| SCHEMBL7205007 | 0.78 | KMT2A (0.38) | LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |