Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7205084

NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@@H](N)CC(=O)OCc1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.53
MMP1 P03956 3/20 0.53
MMP3 P08254 2/20 0.53
CTSS P25774 6/20 0.47
CTSB P07858 3/20 0.47
CTSL P07711 3/20 0.47
CTSK P43235 2/20 0.47
LTA4H P09960 1/20 0.46
CASP1 P29466 1/20 0.43
KLKB1 P03952 1/20 0.43
FCER2 P06734 1/20 0.42
F2R P25116 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL9439523 0.81 MMP1 (0.49) MMP1CTSSCTSBCTSLCTSK
Trifluoroacetic Acid SCHEMBL7206393 0.79 IDO1 (0.46) CTSSCTSBCTSLCTSKCASP1
Hydrochloric Acid SCHEMBL7205077 0.79 CTSL (0.55) MMP1CTSSCTSBCTSLCTSK
Trifluoroacetic Acid SCHEMBL7607303 0.76 SLC15A1 (0.49) CTSLCTSK
Trifluoroacetic Acid SCHEMBL7607313 0.76 SLC15A1 (0.49) CTSLCTSK
SCHEMBL9825723 0.75 EPHX1 (0.57)
SCHEMBL9826358 0.75 EPHX1 (0.57)
SCHEMBL7298200 0.75 SLC15A1 (0.55) MMP1CTSSCTSBCTSLCTSK
SCHEMBL30375020 0.75 SLC15A1 (0.58) CTSL
Trifluoroacetic Acid SCHEMBL966704 0.75 CTSL (0.51) CTSLCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030831-A4 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES AVENTIS PHARM PROD INC (US) 2003-01-02 EP disclosed
US-6180759-B1 PREPARING AZACYCLOALKANOYLPSEUDOTETRAPEPTIDES COMPRISING COUPLING A DIPEPTIDE WITH A PSEUDODIPEPTIDE; FOR EXAMPLE, N-(N-ETHYL-N-(1-OXO-4-(4-PIPERIDINYL)BUTYL)GLYCYL)-(L)-ALPHA-ASPARTYL-3 -CYCLOHEXYL-(L)-ALANINEAMIDE; USE AS ANTICOAGULANTS AVENTIS PHARMACEUTICALS PRODUCTS INC. 2001-01-30 US disclosed
EP-1030831-A1 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES Aventis Pharmaceuticals Products Inc. (US) 2000-08-30 EP disclosed
WO-1999019294-A1 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES AVENTIS PHARMACEUTICALS PRODUCTS INC. LEGAL/PATENTS (US) 1999-04-22 WO disclosed