SCHEMBL7205104

SCHEMBL7205104

O=C(Oc1ccccc1)c1ccc2ccccc2c1C(=O)Oc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
KDM4E B2RXH2 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
NR4A2 P43354 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 1/20 0.50
ALDH1A1 P00352 3/20 0.48
WDR5 P61964 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
ADRA1A P35348 1/20 0.46
KDR P35968 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687756 0.92 MAPT (0.51) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL11678737 0.92 WDR5 (0.54) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL7205110 0.92 KDM4E (0.54) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL3682069 0.87 MAPT (0.53) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL22610047 0.85 WDR5 (0.62) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL27607 0.83 LDHA (0.64) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL29361815 0.83 LDHA (0.64) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL2535220 0.83 ABCG2 (0.51) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL29134061 0.82 MAPT (0.54) MAPTKDM4ETDP1NR4A2HPGD
SCHEMBL2462911 0.81 KDM4E (0.71) MAPTKDM4ETDP1NR4A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029733-B Polyethylene-2, 6-naphthalate composition having excellent blow moldability and molded article thereof 帝人株式会社 2018-09-07 CN disclosed
US-10017629-B2 Polyethylene-2,6-naphthalate composition with excellent blow moldability, and molded product thereof TEIJIN LIMITED (JP) 2018-07-10 US disclosed
EP-3109271-B1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF TEIJIN LTD (JP) 2018-03-28 EP disclosed
EP-3109271-A1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF Teijin Limited (JP) 2016-12-28 EP disclosed
US-20160347934-A1 POLYETHYLENE-2,6-NAPHTHALATE COMPOSITION WITH EXCELLENT BLOW MOLDABILITY, AND MOLDED PRODUCT THEREOF TEIJIN LIMITED (JP) 2016-12-01 US disclosed
EP-1114841-B1 PROCESS FOR PRODUCING POLYARYLATE TEIJIN LTD (JP) 2003-10-08 EP disclosed
US-6417291-B1 CONDENSATION POLYMERIZATION AND ESTERIFICATION OF AROMATIC DIOL AND ESTER-FORMING MONOMER; ENDCAPPING WITH SALICYLIC ACID ESTER DERIVATIVE TEIJIN LIMITED (JP) 2002-07-09 US disclosed
EP-1114841-A1 PROCESS FOR PRODUCING POLYARYLATE TEIJIN LIMITED (JP) 2001-07-11 EP disclosed
US-5516855-A POLYMERIZATION OF AROMATIC DIESTERS, DIAMINES AND DIALCOHOLS FOR BLOCK COPOLYMERS FOR TOUGHNESS GENERAL ELECTRIC COMPANY (US) 1996-05-14 US disclosed
US-5340885-A Tough block polymers GENERAL ELECTRIC COMPANY (US) 1994-08-23 US disclosed
US-5089600-A Molding materials, toughness GENERAL ELECTRIC COMPANY (US) 1992-02-18 US disclosed
US-4876317-A FROM MELT INTERCHANGE OF DIARYL ESTERS OF CARBONIC ACID AND DICARBOXYLIC ACIDS; TOUGH MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1989-10-24 US disclosed
EP-0315026-A2 Copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP disclosed
EP-0315025-A1 Amide-imide copolymers and process for the preparation thereof GENERAL ELECTRIC COMPANY (US) 1989-05-10 EP disclosed
US-4296218-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1981-10-20 US disclosed
US-4251649-A COMPRISING A LOW MOLECULAR WEIGHT MODIFIER POLYESTER AND A POLYFUNCTIONAL HYDROXY OR AMINE TEIJIN LIMITED (JP) 1981-02-17 US disclosed
US-4220563-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1980-09-02 US disclosed
US-4137221-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1979-01-30 US disclosed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US disclosed
US-4031165-A BLOCK COPOLYMER TEIJIN LIMITED (JA) 1977-06-21 US disclosed