Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008912 | 0.84 | ESR1 (0.48) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL22610047 | 0.83 | WDR5 (0.62) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL7205104 | 0.82 | MAPT (0.56) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL27607 | 0.82 | LDHA (0.64) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL29361815 | 0.82 | LDHA (0.64) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL485599 | 0.81 | WDR5 (0.68) | KDM4ENR4A2HPGDALOX15NCEH1 | |
| SCHEMBL7205110 | 0.81 | KDM4E (0.54) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL2606588 | 0.80 | NCEH1 (0.53) | MAPTKDM4ENR4A2HPGDNCEH1 | |
| SCHEMBL2462911 | 0.80 | KDM4E (0.71) | MAPTKDM4ETDP1NR4A2HPGD | |
| SCHEMBL30732496 | 0.79 | HSD17B10 (0.62) | MAPTKDM4ETDP1NR4A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116988078-A | Metal catalyzed asymmetric coupling method promoted by electrochemical reduction | 中国科学院上海有机化学研究所 | 2023-11-03 | — | — | CN | disclosed |