Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200585 | 0.89 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL5010980 | 0.87 | GABRA1 (0.54) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL170049 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1ADRA2CADRA2A | |
| SCHEMBL31201870 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1ADRA2CADRA2A | |
| SCHEMBL2469944 | 0.79 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL28973499 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2AKR1B1ADRA2CADRA2A | |
| SCHEMBL28194954 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2AKR1B1ADRA2CADRA2A | |
| SCHEMBL9269358 | 0.78 | GABRA1 (0.55) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL27313389 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1MEN1KMT2A | |
| SCHEMBL5832429 | 0.76 | FOLH1 (0.47) | GABRA1GABRB2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |