Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 1.00 |
| ▸ | BCL9 | O00512 | 3/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | PTGES | O14684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PNLIP | P16233 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525550 | 1.00 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL6658577 | 0.89 | FDPS (0.80) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL32659910 | 0.83 | FDPS (0.70) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Pisiferol SCHEMBL27950408 | 0.82 | FDPS (0.70) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Pisiferol SCHEMBL30298475 | 0.82 | FDPS (0.70) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL12590737 | 0.78 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL9923661 | 0.78 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL13309664 | 0.78 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL29390188 | 0.78 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL18290359 | 0.78 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2083809-B1 | DIETARY OR PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES FOR THE TREATMENT OF DEPRESSION. | DSM IP ASSETS BV (NL) | 2014-05-07 | — | — | EP | claimed |
| US-8552055-B2 | Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivates and their uses | DSM IP ASSETS B.V. (NL) | 2013-10-08 | — | — | US | claimed |
| US-20100099753-A1 | Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivates and their uses | DSM IP ASSETS B.V. (NL) | 2010-04-22 | — | — | US | claimed |
| US-20100056615-A1 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | DSM IP ASSETS B.V. (NL) | 2010-03-04 | — | — | US | claimed |
| US-20090099251-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2009-04-16 | — | — | US | claimed |
| EP-1925302-A1 | Dietary or pharmaceutical compositions containing tricyclic diterpenes and derivatives thereof for the treatment of depression | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | claimed |
| EP-1925301-A1 | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | claimed |
| EP-4114383-B1 | TRICYCLIC DITERPENE ISOLATED FROM PINE ROSIN FOR THE TREATMENT OF PAIN AND INFLAMMATION | UNIV SOUTH FLORIDA (US) | 2023-08-09 | — | — | EP | disclosed |
| US-8748491-B2 | Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivatives and their uses | DSM IP ASSETS B.V. (NL) | 2014-06-10 | — | — | US | disclosed |
| EP-2083809-B1 | DIETARY OR PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES FOR THE TREATMENT OF DEPRESSION. | DSM IP ASSETS BV (NL) | 2014-05-07 | — | — | EP | disclosed |
| US-20140005270-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2014-01-02 | — | — | US | disclosed |
| JP-2013255495-A | COMPOSITION COMPRISING CARNOSIC ACID 12-METHYLETHER | DSM IP ASSETS BV | 2013-12-26 | — | — | JP | disclosed |
| JP-2013227328-A | USE OF TRICYCLIC DITERPENE AND THE DERIVATIVE FOR TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDER AND/OR JOINT DISORDER | DSM IP ASSETS BV | 2013-11-07 | — | — | JP | disclosed |
| US-20090099251-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2009-04-16 | — | — | US | disclosed |
| WO-2008061754-A1 | DIETARY OR PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND DERIVATIVES THEREOF FOR THE TREATMENT OF DEPRESSION | DSM IP ASSETS B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008061720-A2 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | DSM IP ASSETS B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| EP-1925302-A1 | Dietary or pharmaceutical compositions containing tricyclic diterpenes and derivatives thereof for the treatment of depression | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925301-A1 | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925301-A1 | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925301-A1 | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders | DSMIP Assets B.V. (NL) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099753-A1 | Dietary and pharmaceutical compositions containing tricyclic diterpenes and their derivates and their uses | CHRM1, CYP8B1, OXER1 | FDPS 1255/4885BCL9 2901/4885CTNNB1 2674/4885 |
| US-20090099251-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | CHRM1, CYP8B1, OXER1 | FDPS 1222/4885BCL9 2989/4885CTNNB1 2588/4885 |
| US-20140005270-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS CONTAINING TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | CHRM1, CYP8B1, HCRTR1 | FDPS 1192/4885BCL9 2950/4885CTNNB1 2741/4885 |
| US-20100056615-A1 | USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS | TNF, VDR, CYP24A1 | FDPS 56/4885BCL9 2980/4885CTNNB1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.