Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 16/20 | 1.00 |
| ▸ | BCL9 | O00512 | 3/20 | 1.00 |
| ▸ | CTNNB1 | P35222 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | PTGES | O14684 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | PNLIP | P16233 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | GSTO1 | P78417 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carnosic Acid SCHEMBL29390188 | 1.00 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL12590737 | 1.00 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL18290359 | 1.00 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Carnosic Acid SCHEMBL9923661 | 1.00 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL29405917 | 0.89 | FDPS (0.80) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL9923660 | 0.89 | FDPS (0.80) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL15031243 | 0.89 | FDPS (0.80) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| Methyl Carnosate SCHEMBL29426661 | 0.88 | FDPS (1.00) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL15031246 | 0.86 | FDPS (0.76) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 | |
| SCHEMBL1439596 | 0.83 | FDPS (0.71) | FDPSBCL9CTNNB1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | NUTECH VENTURES | 2016-10-27 | — | — | US | disclosed |
| US-20120296112-A1 | Neuroprotective Compositions and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-22 | — | — | US | disclosed |
| EP-1664262-B1 | THE USE OF LABIATAE HERB PREPARATIONS FOR FOAM ENCHANCEMENT OF BEVERAGES | KALAMAZOO HOLDINGS INC (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2008061756-A1 | DIETARY AND PHARMACEUTICAL COMPOSITIONS COMPRISING A SAGE EXTRACT CONTAINING A MIXTURE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES AND THEIR USES | DSM IP ASSETS B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310528-A1 | Castration-Resistant Prostate Cancer | UGDH, G6PD, DPYD | FDPS 538/4885BCL9 4548/4885CTNNB1 2408/4885 |
| US-20120296112-A1 | Neuroprotective Compositions and Methods | KEAP1, NFE2L2, NQO1 | FDPS 1051/4885BCL9 4556/4885CTNNB1 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.