⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763485 | 0.73 | ADORA2B (0.32) | — | |
| SCHEMBL11497636 | 0.69 | ADORA2B (0.39) | — | |
| SCHEMBL14204019 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL32680041 | 0.67 | POLB (0.47) | — | |
| SCHEMBL6357875 | 0.67 | — | — | |
| SCHEMBL11245537 | 0.66 | CYP3A4 (0.46) | — | |
| SCHEMBL11129479 | 0.64 | CYP1A2 (0.49) | — | |
| SCHEMBL14364186 | 0.63 | ADORA2B (0.30) | — | |
| SCHEMBL11846055 | 0.62 | — | — | |
| Alcohol SCHEMBL11368781 | 0.62 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339709-A1 | FARNESYL TRANSFERASE INHIBITING BENZOHETEROCYCLIC DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002042296-A1 | FARNESYL TRANSFERASE INHIBITING BENZOHETEROCYCLIC DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-05-30 | — | — | WO | disclosed |
| EP-0701172-B1 | A method for making imaging elements suitable for use in the silver salt diffusion transfer process | AGFA GEVAERT NV (BE) | 1999-10-27 | — | — | EP | disclosed |
| EP-0701172-A1 | A method for making imaging elements suitable for use in the silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1996-03-13 | — | — | EP | disclosed |
| US-4543309-A | BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-09-24 | — | — | US | disclosed |