SCHEMBL32680041

SCHEMBL32680041

C=CCn1cnnc1-c1ccncc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ HTT P42858 1/20 0.42
▸ MAPK9 P45984 1/20 0.39
▸ MAPK10 P53779 1/20 0.39
▸ HDAC2 Q92769 3/20 0.38
▸ HDAC1 Q13547 2/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ PTK2 Q05397 2/20 0.37
▸ HDAC8 Q9BY41 2/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ HDAC3 O15379 1/20 0.36
▸ HDAC6 Q9UBN7 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ ALDH1A1 P00352 4/20 0.36
▸ HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2889930 0.77 L3MBTL1 (0.53) L3MBTL1MAPK9MAPK10SMN1; SMN2KMT2A
SCHEMBL11033647 0.74 RAB9A (0.32) SMN1; SMN2ALDH1A1
SCHEMBL20472009 0.68 ASIC3 (0.37) SMN1; SMN2KMT2AHSD17B10ALDH1A1HPGD
SCHEMBL2451213 0.67 L3MBTL1 (0.49) L3MBTL1MAPK9MAPK10SMN1; SMN2KMT2A
SCHEMBL7205591 0.67 — —
SCHEMBL7512001 0.67 QPCTL (0.58) L3MBTL1HTTSMN1; SMN2KMT2AUSP2
SCHEMBL8763485 0.66 ADORA2B (0.32) —
SCHEMBL10556278 0.65 ALDH1A1 (0.55) POLBL3MBTL1HTTSMN1; SMN2KMT2A
SCHEMBL8840725 0.65 POLB (0.41) POLBL3MBTL1HTTSMN1; SMN2KMT2A
SCHEMBL19219072 0.65 L3MBTL1 (0.46) L3MBTL1MAPK9MAPK10MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564547-B2 Compositions, formulations, and methods for skin treatment ODDITY LABS, LLC (US) 2026-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564547-B2 Compositions, formulations, and methods for skin treatment MCOLN1, H1-0, APOL1 POLB 4098/4885L3MBTL1 503/4885HTT 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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