Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL28185054 | 0.87 | HDAC3 (0.53) | TDP1POLBAPEX1HTTGLA | |
| Styrene SCHEMBL9305623 | 0.85 | TDP1 (0.43) | TDP1POLBAPEX1HTTGLA | |
| Styrene SCHEMBL409075 | 0.85 | TDP1 (0.43) | TDP1POLBAPEX1HTTGLA | |
| SCHEMBL5843377 | 0.85 | TDP1 (0.44) | TDP1POLBAPEX1HTTGLA | |
| SCHEMBL4968472 | 0.84 | PPARG (0.39) | TDP1POLBAPEX1HTTGLA | |
| SCHEMBL9305618 | 0.84 | PAM (0.45) | TDP1POLBAPEX1HTTGLA | |
| SCHEMBL8171290 | 0.84 | POLB (0.40) | TDP1POLBAPEX1HTTGLA | |
| Styrene SCHEMBL11239895 | 0.83 | TDP1 (0.41) | TDP1POLBAPEX1HTTGLA | |
| Styrene SCHEMBL28447649 | 0.83 | TDP1 (0.41) | TDP1POLBAPEX1HTTGLA | |
| SCHEMBL1506674 | 0.83 | TDP1 (0.37) | TDP1POLBAPEX1HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610282-B1 | Biologically active compounds that slowly release the biologically active compound. These compositions may be directly incorporated into the locus to be protected or may be applied to a structure in a coating. | ROHM AND HAAS COMPANY | 2003-08-26 | — | — | US | claimed |