Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 12/20 | 0.63 |
| ▸ | CASP3 | P42574 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928398 | 0.88 | CASP1 (0.65) | CASP1CASP3 | |
| SCHEMBL6830955 | 0.85 | CASP1 (0.59) | CASP1CASP3TDP1LMNA | |
| SCHEMBL6832920 | 0.85 | CASP3 (0.59) | CASP1CASP3TDP1CASP6CASP8 | |
| SCHEMBL5496227 | 0.83 | CASP3 (0.75) | CASP1CASP3TDP1CASP6CASP8 | |
| SCHEMBL8356276 | 0.83 | CASP3 (0.57) | CASP1CASP3TDP1CASP6CASP8 | |
| SCHEMBL6832897 | 0.81 | CASP3 (0.61) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL6832898 | 0.81 | CASP3 (0.61) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL6830917 | 0.81 | CASP3 (0.48) | CASP1CASP3TDP1CASP6CASP8 | |
| SCHEMBL16312242 | 0.80 | LMNA (0.54) | TDP1LMNA | |
| SCHEMBL14598421 | 0.80 | CASP3 (0.62) | CASP1CASP3TDP1CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003072528-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | CASP1 5/4885CASP3 3/4885TDP1 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.