Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3783189 | 0.97 | HTR2A (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL8854555 | 0.83 | HTR2A (0.36) | HTR2AGPR3 | |
| Hydrochloric Acid SCHEMBL8927357 | 0.82 | HTR2A (0.32) | HTR2APOLB | |
| SCHEMBL8366223 | 0.79 | POLB (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL2353823 | 0.78 | HTR2A (0.33) | HTR2A | |
| Hydrochloric Acid SCHEMBL7592112 | 0.77 | POLB (0.34) | HTR2APOLBGPR3 | |
| SCHEMBL7600618 | 0.77 | POLB (0.38) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7095854 | 0.77 | POLB (0.34) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7128017 | 0.75 | WDR5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7125703 | 0.73 | IL1R1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891382-B1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LTD (JP) | 2003-05-28 | — | — | EP | disclosed |