Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7205884 | 0.97 | HTR2A (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL8854555 | 0.86 | HTR2A (0.36) | HTR2AGPR3CYP1A2CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL8927357 | 0.85 | HTR2A (0.32) | HTR2APOLBCYP1A2CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL2353823 | 0.81 | HTR2A (0.33) | HTR2A | |
| Hydrochloric Acid SCHEMBL7095854 | 0.81 | POLB (0.34) | HTR2APOLBGPR3CYP1A2CYP3A4 | |
| SCHEMBL8366223 | 0.79 | POLB (0.35) | HTR2APOLBGPR3CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7128017 | 0.78 | WDR5 (0.33) | — | |
| SCHEMBL7600618 | 0.77 | POLB (0.38) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7592112 | 0.77 | POLB (0.34) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7125703 | 0.75 | IL1R1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920465-B1 | ELASTOMERIC CYCLOOLEFINPOLYMER | TICONA GMBH (DE) | 2002-11-06 | — | — | EP | claimed |
| US-5696045-A | USING MIXTURE OF ZIRCONOCENE CATALYSTS | TARGOR GMBH (DE) | 1997-12-09 | — | — | US | claimed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | claimed |
| CN-113543971-B | Adhesive body, method for assembling adhesive body, and method for removing adhesive body | DIC株式会社 | 2023-12-01 | — | — | CN | disclosed |
| CN-113543971-A | Adhesive body, method for assembling adhesive body, and method for disassembling adhesive body | DIC株式会社 | 2021-10-22 | — | — | CN | disclosed |
| WO-2020195884-A1 | BONDED BODY, BONDED BODY ASSEMBLY METHOD, AND BONDED BODY DISASSEMBLY METHOD | DIC株式会社 | 2020-10-01 | — | — | WO | disclosed |
| EP-2204375-A1 | Preparation of mono-aryl-substituted methylene-bridged substituted cyclopentadienyl-fluorenyl ligands and zirconium complexes derived thereof | Total Petrochemicals Research Feluy (BE) | 2010-07-07 | — | — | EP | disclosed |
| US-20080069973-A1 | Retardation Film | TEIJIN LIMITED (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1791005-A1 | RETARDATION FILM | TEIJIN LIMITED (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-20050271851-A1 | Release agent, adhesive laminate and adhesive laminated tape | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-12-08 | — | — | US | disclosed |
| US-20050266256-A1 | Release agent and release sheet | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-12-01 | — | — | US | disclosed |
| EP-1555304-A1 | RELEASE AGENT AND RELEASE SHEET | Mitsubishi Chemical Corporation (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-0891382-B1 | ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION | TEIJIN LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0920465-B1 | ELASTOMERIC CYCLOOLEFINPOLYMER | TICONA GMBH (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6476153-B2 | INCLUDES A STEP OF DISTILLING UNREACTED DICYCLOPENTADIENE OR HYDROGENATED PRODUCT THEREOF, TETRAHYDRODICYCLOPENTADIENE FROM A MIXTURE OF THE COPOLYMER OR ITS HYDROGENATED PRODUCT IN THE PRESENCE OF A HIGH BOILING HYDROCARBON SOLVENT | TEIJIN LIMITED (JP) | 2002-11-05 | — | — | US | disclosed |
| US-6388032-B1 | SEPARATION BY FILTRATION | TEIJIN LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |
| US-20010009950-A1 | Process for producing hydrogenated alpha-olefin- dicyclopentadiene copolymer, method for molding the same and optical material | HASHIDZUME KIYONARI (JP) | 2001-07-26 | — | — | US | disclosed |
| EP-1028128-A1 | CYCLOOLEFIN POLYMER REDUCED IN CATALYST RESIDUE CONTENT, USE THEREOF, AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0964005-A1 | Process for producing hydrogenated alpha-olefin-dicyclopentadiene copolymer, method for molding the same and optical material | TEIJIN LIMITED (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |