Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206750 | 0.92 | CXCL12 (0.45) | HSD17B10ALDH1A1TSHRKDM4ESIRT2 | |
| SCHEMBL2060381 | 0.87 | CPB1 (0.48) | HSD17B10ALDH1A1POLBCPB1TSHR | |
| SCHEMBL2060168 | 0.86 | L3MBTL1 (0.45) | HSD17B10ALDH1A1POLBTSHRKDM4E | |
| SCHEMBL7208339 | 0.86 | ADORA3 (0.48) | ALDH1A1POLBTSHRMAPK1LMNA | |
| SCHEMBL10174463 | 0.85 | L3MBTL1 (0.48) | HSD17B10ALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL2060503 | 0.85 | SIRT2 (0.44) | ALDH1A1POLBSIRT2LMNA | |
| SCHEMBL2060142 | 0.85 | ABCB1 (0.56) | HSD17B10TP53ALDH1A1TSHRKDM4E | |
| SCHEMBL7210239 | 0.85 | ABCB1 (0.50) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL7209553 | 0.85 | TSHR (0.44) | HSD17B10ALDH1A1POLBTSHRKDM4E | |
| SCHEMBL2060280 | 0.84 | ABCB1 (0.41) | HSD17B10ALDH1A1CPB1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |