Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679578 | 0.87 | TSHR (0.36) | TSHRALDH1A1FAAHNPC1S1PR2 | |
| Ethane SCHEMBL260368 | 0.77 | — | — | |
| SCHEMBL3512818 | 0.77 | — | — | |
| SCHEMBL23101 | 0.77 | — | — | |
| SCHEMBL8764182 | 0.77 | — | — | |
| SCHEMBL547567 | 0.76 | ALDH1A1 (0.50) | TSHRALDH1A1FAAHNPC1S1PR2 | |
| Ether SCHEMBL4291703 | 0.74 | CA1 (0.32) | TSHRALDH1A1CA2CA1 | |
| SCHEMBL10639166 | 0.74 | FAAH (0.50) | TSHRALDH1A1FAAHTHRBNPC1 | |
| SCHEMBL22894669 | 0.74 | FAAH (0.50) | TSHRALDH1A1FAAHTHRBNPC1 | |
| SCHEMBL11333957 | 0.74 | FAAH (0.50) | TSHRALDH1A1FAAHTHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013861-A1 | ANTI-FCRH5 ANTIBODIES | Genentech, Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014210064-A1 | ANTI-FCRH5 ANTIBODIES | GENENTECH, INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20030035786-A1 | Biological tissue adhesives, articles, and methods | MEDTRONIC, INC. | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030035786-A1 | Biological tissue adhesives, articles, and methods | ICAM1, EPCAM, VCAM1 | TSHR 2816/4885ALDH1A1 706/4885FAAH 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.