Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172042 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19ALDH1A1MAPTKDM4E | |
| SCHEMBL7180775 | 0.80 | EPHX1 (0.44) | SMN1; SMN2CYP2C19ALDH1A1L3MBTL1ATM | |
| SCHEMBL17497929 | 0.75 | CYP2C19 (0.50) | SMN1; SMN2CYP2C19ALDH1A1L3MBTL1ATM | |
| SCHEMBL17497933 | 0.75 | CYP2C19 (0.50) | SMN1; SMN2CYP2C19ALDH1A1L3MBTL1ATM | |
| SCHEMBL6930122 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL7169372 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL6930120 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL7210773 | 0.73 | SIGMAR1 (0.64) | CYP2C19ALOX15SIGMAR1TSHRMEN1 | |
| SCHEMBL10526965 | 0.73 | RIPK1 (0.49) | KDM4EL3MBTL1MAPK1EPHX2RIPK1 | |
| SCHEMBL15957077 | 0.71 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | claimed |