Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL7083184 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRCA5ACA5BTHRB | |
| Ether SCHEMBL502338 | 0.88 | — | — | |
| 2-Ethoxyethanol SCHEMBL10613720 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRCA5ACA5BTHRB | |
| SCHEMBL325926 | 0.79 | — | — | |
| SCHEMBL1774061 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRTHRBLMNA | |
| SCHEMBL25425853 | 0.76 | — | — | |
| Nitric Acid SCHEMBL27957404 | 0.76 | — | — | |
| Nitric Acid SCHEMBL2217977 | 0.75 | CA5A (0.67) | ALDH1A1TSHRCA5ACA5BLMNA | |
| Nitric Acid SCHEMBL1587834 | 0.75 | — | — | |
| Nitric Acid SCHEMBL2217867 | 0.75 | CA5A (0.67) | ALDH1A1TSHRCA5ACA5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607618-B1 | Munitions propellant. The propellant has a nitrocellulose component is about fifty-two percent (52.0%) of the propellant. This is either a nitrocellulose having twelve and six-tenths percent (12.6%) nitrogen, or a combination of a | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2003-08-19 | — | — | US | claimed |