Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513769 | 0.81 | ALOX5 (0.82) | ALOX5HTR2BHTR7KDM4ETDP1 | |
| SCHEMBL28406723 | 0.74 | ALOX5 (0.67) | ALOX5HTR2BHTR7KDM4EGAA | |
| SCHEMBL2483714 | 0.73 | ALOX5 (1.00) | ALOX5HTR2BHTR7TDP1GAA | |
| SCHEMBL30812968 | 0.73 | ALOX5 (1.00) | ALOX5HTR2BHTR7TDP1GAA | |
| SCHEMBL28403621 | 0.71 | ALOX5 (0.79) | ALOX5HTR2BHTR7KDM4EGAA | |
| Phenoxazine SCHEMBL6270610 | 0.66 | ALOX5 (0.77) | ALOX5HTR2BHTR7TDP1LMNA | |
| SCHEMBL26115655 | 0.66 | ALOX5 (0.84) | ALOX5HTR2BHTR7MEN1KMT2A | |
| SCHEMBL28400911 | 0.65 | ALOX5 (0.83) | ALOX5HTR2BHTR7KDM4ETDP1 | |
| Bicarbonate SCHEMBL6271245 | 0.64 | ALOX5 (0.56) | ALOX5HTR2BHTR7KDM4ETDP1 | |
| SCHEMBL5115778 | 0.64 | HTR2B (0.62) | ALOX5HTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610686-B1 | Administering onto corneal tissue topical opthalmic drug comprising 1-hydroxy-5-oxo-5H-pyrido-phenoxazin-3-carboxylic acid (pirenoxine) or pharmaceutically acceptable salt for protection of corneal tissue in photokeratectomy intervention | AUSIMONT S.P.A. (IT) | 2003-08-26 | — | — | US | claimed |