Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 1.00 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483714 | 1.00 | ALOX5 (1.00) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| SCHEMBL28400911 | 0.91 | ALOX5 (0.83) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| SCHEMBL2513769 | 0.90 | ALOX5 (0.82) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| SCHEMBL28403621 | 0.88 | ALOX5 (0.79) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| SCHEMBL4859644 | 0.85 | ALOX5 (0.74) | ALOX5HTR2BHTR7GAAMAPT | |
| SCHEMBL4748216 | 0.83 | ALOX5 (0.71) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| Phenoxazine SCHEMBL6270610 | 0.82 | ALOX5 (0.77) | ALOX5HTR2BHTR7GAAMAPT | |
| SCHEMBL1928583 | 0.81 | ALOX5 (0.68) | ALOX5HTR2BHTR7ALDH1A1MAPK1 | |
| SCHEMBL28406723 | 0.80 | ALOX5 (0.67) | ALOX5HTR2BHTR7GAAALDH1A1 | |
| SCHEMBL18288092 | 0.78 | ALOX5 (0.64) | ALOX5GAAALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092744-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | THE NATIONAL INSTITUTES OF PHARMACEUTICAL R&D CO., LTD (CN) | 2024-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092744-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GOT2, HADH, CYP4A11 | ALOX5 113/4885HTR2B 1543/4885HTR7 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.