Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194020 | 1.00 | LMNA (0.42) | LMNAADKALDH1A1TSHRMAPT | |
| SCHEMBL7210851 | 0.89 | LMNA (0.45) | LMNAADKALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8198893 | 0.89 | LMNA (0.45) | LMNAADKALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8198789 | 0.88 | LMNA (0.46) | LMNAADKSMN1; SMN2 | |
| SCHEMBL7209555 | 0.88 | LMNA (0.46) | LMNAADKSMN1; SMN2 | |
| SCHEMBL7204636 | 0.87 | LMNA (0.56) | LMNAADKALDH1A1TSHRMAPT | |
| SCHEMBL8197032 | 0.87 | LMNA (0.56) | LMNAADKALDH1A1TSHRMAPT | |
| SCHEMBL3817191 | 0.86 | LMNA (0.51) | LMNAADKALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8193476 | 0.85 | NAAA (0.46) | LMNAADKTDP1ACHE | |
| SCHEMBL7210256 | 0.85 | NAAA (0.46) | LMNAADKTDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |