Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193476 | 1.00 | NAAA (0.46) | NAAALMNAADKACHEBCHE | |
| SCHEMBL8193927 | 0.89 | LMNA (0.49) | NAAALMNAADKTDP1 | |
| SCHEMBL7205814 | 0.89 | LMNA (0.49) | NAAALMNAADKTDP1 | |
| SCHEMBL7206540 | 0.87 | LMNA (0.58) | NAAALMNAADK | |
| SCHEMBL8192195 | 0.87 | LMNA (0.58) | NAAALMNAADK | |
| SCHEMBL3821749 | 0.86 | LMNA (0.56) | LMNAADK | |
| SCHEMBL8193747 | 0.85 | LMNA (0.49) | NAAALMNAADKTDP1 | |
| SCHEMBL7209654 | 0.85 | LMNA (0.49) | NAAALMNAADKTDP1 | |
| SCHEMBL3821461 | 0.85 | LMNA (0.59) | LMNAADKBCHETDP1 | |
| SCHEMBL8194020 | 0.85 | LMNA (0.42) | LMNAADKACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |