Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194085 | 1.00 | LMNA (0.44) | LMNATDP1ADKTHRBSMN1; SMN2 | |
| SCHEMBL3817191 | 0.89 | LMNA (0.51) | LMNATDP1ADKTHRBSMN1; SMN2 | |
| SCHEMBL7208717 | 0.88 | LMNA (0.42) | LMNATDP1ADK | |
| SCHEMBL7204677 | 0.88 | LMNA (0.42) | LMNATDP1ADK | |
| SCHEMBL8193895 | 0.88 | LMNA (0.42) | LMNATDP1ADK | |
| SCHEMBL7205985 | 0.87 | LMNA (0.58) | LMNAADK | |
| SCHEMBL8196428 | 0.87 | LMNA (0.58) | LMNAADK | |
| SCHEMBL3821749 | 0.87 | LMNA (0.56) | LMNAADKTHRBSMN1; SMN2HIF1A | |
| SCHEMBL3817265 | 0.87 | LMNA (0.46) | LMNATDP1ADKTHRBSMN1; SMN2 | |
| SCHEMBL7205230 | 0.86 | LMNA (0.40) | LMNATDP1THRBSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | claimed |
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |