Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820421 | 0.89 | LMNA (0.49) | LMNATDP1ADK | |
| SCHEMBL8193930 | 0.88 | LMNA (0.56) | LMNAADK | |
| SCHEMBL7205842 | 0.88 | LMNA (0.56) | LMNAADK | |
| SCHEMBL8194085 | 0.88 | LMNA (0.44) | LMNATDP1ADK | |
| SCHEMBL7206807 | 0.88 | LMNA (0.44) | LMNATDP1ADK | |
| SCHEMBL3818930 | 0.87 | LMNA (0.44) | LMNATDP1ADK | |
| SCHEMBL3817626 | 0.87 | LMNA (0.57) | LMNAADK | |
| SCHEMBL8193895 | 0.85 | LMNA (0.42) | LMNATDP1ADK | |
| SCHEMBL7204677 | 0.85 | LMNA (0.42) | LMNATDP1ADK | |
| SCHEMBL3819094 | 0.80 | LMNA (0.58) | LMNAADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | claimed |
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |