Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597451 | 0.81 | HTT (0.39) | NAMPTTBXAS1MPOMAPTHTT | |
| SCHEMBL5597308 | 0.78 | NAMPT (0.36) | NAMPTXDHNPC1RAB9ATBXAS1 | |
| SCHEMBL4642038 | 0.73 | NAMPT (0.36) | NAMPTNPC1RAB9ATBXAS1MPO | |
| SCHEMBL4642071 | 0.73 | LRRK2 (0.39) | XDHNPC1RAB9AHTTKDM4E | |
| SCHEMBL4642509 | 0.72 | MRGPRX4 (0.42) | MAPTKDM4ESLC6A4LMNASMN1; SMN2 | |
| SCHEMBL5597314 | 0.71 | LRRK2 (0.37) | XDHNPC1RAB9ATBXAS1HTT | |
| SCHEMBL5597420 | 0.71 | MRGPRX4 (0.40) | MAPTKDM4ESLC6A4LMNASMN1; SMN2 | |
| SCHEMBL7206819 | 0.71 | XDH (0.35) | XDHNPC1RAB9AMAPTHTT | |
| SCHEMBL11701063 | 0.66 | TAAR1 (0.53) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5597242 | 0.65 | SLC6A4 (0.43) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082299-A1 | IMPROVED HORMONE REPLACEMENT THERAPY | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |