Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597314 | 0.92 | LRRK2 (0.37) | LRRK2CCR5SLC6A4MAOAMAOB | |
| SCHEMBL5597242 | 0.81 | SLC6A4 (0.43) | CCR5SLC6A4MAOB | |
| SCHEMBL4642232 | 0.80 | RXRA (0.44) | XDH | |
| SCHEMBL4642509 | 0.80 | MRGPRX4 (0.42) | SLC6A4KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL5597306 | 0.75 | SMPD1 (0.41) | — | |
| SCHEMBL11702689 | 0.75 | CCR5 (0.48) | CCR5ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL6437512 | 0.75 | LRRK2 (0.45) | LRRK2KDM4EPOLBHPGDNPC1 | |
| SCHEMBL5597311 | 0.74 | RXRA (0.44) | XDH | |
| SCHEMBL7206821 | 0.73 | NAMPT (0.36) | SLC6A4XDHTDP2KDM4ENPC1 | |
| SCHEMBL5597420 | 0.72 | MRGPRX4 (0.40) | SLC6A4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804805-A4 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | UNIV WAYNE STATE (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1804805-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006041941-A2 | USE OF AROMATASE INHIBITORS FOR THE TREATMENT OF ECTOPIC PREGNANCY | WAYNE STATE UNIVERSITY (US) | 2006-04-20 | — | — | WO | disclosed |