SCHEMBL7206888

SCHEMBL7206888

CCCCCCCCCCCC(=O)c1c(OC(=O)OCC)n(Cc2cccc(/C=C/C(=O)OCC)c2)c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.40
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7213227 0.91 PLA2G2A (0.43) PLA2G2A
SCHEMBL7965541 0.88 PLA2G2A (0.52) PLA2G2A
SCHEMBL7965543 0.88 PLA2G2A (0.52) PLA2G2A
SCHEMBL7206879 0.85 PLA2G2A (0.44) PLA2G2A
SCHEMBL9282528 0.80 GABRA1 (0.44) PLA2G2ACNR2
SCHEMBL9271951 0.79 CNR2 (0.55) PLA2G2ACNR2
SCHEMBL7206874 0.78 PLA2G2A (0.56) PLA2G2A
SCHEMBL7211954 0.78 PLA2G2A (0.56) PLA2G2A
SCHEMBL7211881 0.78 PSEN1 (0.54) PLA2G2ACNR2
SCHEMBL7968970 0.78 PLA2G2A (0.56) PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923546-B1 ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 MERCKLE GMBH (DE) 2003-11-26 EP disclosed
EP-0923546-A1 ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 Merckle GmbH (DE) 1999-06-23 EP disclosed
WO-1998005637-A1 ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A¿2? MERCKLE GMBH (DE) 1998-02-12 WO disclosed