Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169376 | 0.85 | PTGS2 (0.41) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6172018 | 0.83 | PTGS2 (0.44) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6169834 | 0.72 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL6172630 | 0.69 | PTGS2 (0.46) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6171537 | 0.69 | PTGS2 (0.53) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL27554754 | 0.69 | MCL1 (0.46) | PTGS2 | |
| SCHEMBL8138482 | 0.67 | ABCB11 (0.43) | KIF11HPGDRECQL | |
| SCHEMBL6172076 | 0.66 | PTGS2 (0.50) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL6171863 | 0.66 | PTGS2 (0.50) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL27554756 | 0.66 | MCL1 (0.41) | HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |