Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187685 | 0.79 | CYP2C19 (0.46) | CYP2C19HIF1APOLBTAAR1ALDH1A1 | |
| SCHEMBL27361323 | 0.78 | TAAR1 (0.44) | CYP2C19HIF1APOLBKCNN4TAAR1 | |
| SCHEMBL10823218 | 0.78 | CYP2C19 (0.42) | CYP2C19HIF1APOLBKCNN4TAAR1 | |
| SCHEMBL10823220 | 0.78 | CYP2C19 (0.44) | CYP2C19HIF1APOLBKCNN4TAAR1 | |
| SCHEMBL23322503 | 0.76 | TAAR1 (0.41) | CYP2C19HIF1APOLBKCNN4TAAR1 | |
| SCHEMBL10563207 | 0.75 | CYP2C19 (0.48) | CYP2C19HIF1APOLBKCNN4TAAR1 | |
| SCHEMBL873147 | 0.74 | CYP2C19 (0.52) | CYP2C19HIF1AKCNN4TAAR1ALDH1A1 | |
| SCHEMBL57411 | 0.72 | CYP2C19 (0.69) | CYP2C19HIF1AKCNN4TAAR1ALDH1A1 | |
| SCHEMBL24487000 | 0.71 | TSHR (0.48) | ALDH1A1CETPKMT2ATSHR | |
| SCHEMBL11285014 | 0.70 | ALOX15 (0.55) | CYP2C19ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730866-B1 | Treatment of optic nerve disorders with prostanoic acid compounds | R TECH UENO LTD (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-5773471-A | VISION DEFECTS | R-TECH UENO, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0730866-A2 | Treatment of optic nerve disorders with prostanoic acid compounds | R-TECH UENO LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |