Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203539 | 0.96 | LSS (0.38) | LSSGPR119ITGB3ITGA2BDPP4 | |
| SCHEMBL7202897 | 0.81 | LSS (0.45) | LSSDPP4ATF4PPARAELANE | |
| SCHEMBL7207247 | 0.80 | LSS (0.64) | LSSGPR119 | |
| SCHEMBL6019193 | 0.79 | LSS (0.48) | LSSGPR119ITGB3ITGA2B | |
| SCHEMBL6019198 | 0.79 | LSS (0.48) | LSSGPR119ITGB3ITGA2B | |
| SCHEMBL6018945 | 0.79 | ALDH1A1 (0.38) | DPP4ATF4HRH3KMT2A | |
| SCHEMBL6019091 | 0.77 | LSS (0.48) | LSSGPR119 | |
| SCHEMBL6019087 | 0.77 | LSS (0.48) | LSSGPR119 | |
| SCHEMBL6020056 | 0.77 | LSS (0.57) | LSSGPR119 | |
| SCHEMBL6020052 | 0.77 | LSS (0.57) | LSSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |