Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205316 | 0.87 | MMP9 (0.55) | ITGA4MMP9MMP8MMP14PYGL | |
| SCHEMBL7205323 | 0.87 | MMP9 (0.55) | ITGA4MMP9MMP8MMP14PYGL | |
| SCHEMBL7204598 | 0.86 | MAPT (0.51) | F7MMP9MMP8MMP14HDAC1 | |
| SCHEMBL7202948 | 0.86 | MMP9 (0.50) | ITGA4F7MMP9MMP8MMP14 | |
| SCHEMBL7205260 | 0.86 | MMP9 (0.50) | ITGA4MMP9MMP8MMP14PYGL | |
| SCHEMBL7202940 | 0.86 | MMP9 (0.50) | ITGA4F7MMP9MMP8MMP14 | |
| SCHEMBL7205257 | 0.86 | MMP9 (0.50) | ITGA4MMP9MMP8MMP14PYGL | |
| SCHEMBL7203005 | 0.85 | MMP9 (0.55) | MMP9MMP8MMP14PYGLTACR1 | |
| SCHEMBL7203001 | 0.85 | MMP9 (0.55) | MMP9MMP8MMP14PYGLTACR1 | |
| SCHEMBL7203452 | 0.84 | MMP9 (0.48) | ITGA4MMP9MMP8MMP14PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |