Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211881 | 0.87 | PSEN1 (0.54) | PLA2G2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7207563 | 0.83 | PLA2G2A (0.66) | PLA2G2A | |
| SCHEMBL9268492 | 0.78 | PLA2G2A (0.64) | PLA2G2A | |
| SCHEMBL7211985 | 0.77 | PLA2G2A (0.53) | PLA2G2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9266165 | 0.77 | PLA2G2A (0.67) | PLA2G2A | |
| SCHEMBL9268578 | 0.76 | PLA2G2A (0.69) | PLA2G2A | |
| SCHEMBL7968970 | 0.76 | PLA2G2A (0.56) | PLA2G2A | |
| SCHEMBL7968973 | 0.76 | PLA2G2A (0.56) | PLA2G2A | |
| SCHEMBL9271951 | 0.75 | CNR2 (0.55) | PLA2G2A | |
| SCHEMBL9269666 | 0.75 | PLA2G2A (0.67) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |