Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212937 | 0.87 | NPC1 (0.47) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL7207839 | 0.75 | KCNN4 (0.38) | PRSS1CTSGCTRB1CMA1POLB | |
| SCHEMBL7207845 | 0.74 | MEN1 (0.40) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL7212742 | 0.71 | HPRT1 (0.39) | ANPEPERAP1ERAP2 | |
| SCHEMBL27924143 | 0.69 | TSHR (0.50) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL8212160 | 0.68 | ALDH1A1 (0.55) | CA1CA2CA9EPHX2NPC1 | |
| SCHEMBL4268814 | 0.68 | ELANE (0.40) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29006958 | 0.67 | NPC1 (0.50) | CA1CA2MMP1MMP2CA9 | |
| Butane SCHEMBL11539996 | 0.67 | CETP (0.46) | CA1CA2CA9ANPEPERAP1 | |
| SCHEMBL6570293 | 0.67 | POLB (0.48) | S1PR4S1PR1S1PR3S1PR5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |