Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19673900 | 0.75 | ALOX15 (0.41) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL11923135 | 0.75 | BRD4 (0.48) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL28174282 | 0.73 | BRD4 (0.40) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL27827131 | 0.72 | BRD4 (0.42) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL28413210 | 0.72 | MAPK1 (0.47) | HSD17B10BRD4CREBBPMAPK1HSD17B3 | |
| SCHEMBL6261159 | 0.71 | MAOA (0.44) | GAAKDM4EMEN1MAPTKMT2A | |
| SCHEMBL11921167 | 0.71 | BRD4 (0.41) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL14149407 | 0.71 | BRD4 (0.41) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| SCHEMBL27993916 | 0.69 | MAPK1 (0.48) | ALOX15HSD17B10BRD4CREBBPMAPK1 | |
| Hydrochloric Acid SCHEMBL11434377 | 0.69 | MAOA (0.46) | GAAMEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768822-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-12-06 | — | — | EP | disclosed |
| EP-0987255-B1 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |