Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901614 | 0.83 | PPARA (0.50) | PPARAPPARGF2PPARDCA12 | |
| SCHEMBL12442802 | 0.69 | PPARA (0.57) | PPARAPPARGF2PPARDCA12 | |
| SCHEMBL13156122 | 0.69 | PPARA (0.57) | PPARAPPARGF2PPARDCA12 | |
| SCHEMBL979920 | 0.68 | PPARA (0.49) | PPARAPPARGPPARDCA1CA2 | |
| SCHEMBL7772365 | 0.68 | GABRG2 (0.36) | — | |
| SCHEMBL3113325 | 0.68 | NPC1 (0.58) | PPARAPPARGPPARDCA12CA1 | |
| SCHEMBL7858920 | 0.68 | PPARA (0.53) | PPARAPPARGPPARDCA12CA1 | |
| SCHEMBL5729194 | 0.67 | LSS (0.43) | FFAR1FFAR4 | |
| SCHEMBL7861194 | 0.67 | PTGS2 (0.41) | PPARAPPARGF2CA12CA1 | |
| SCHEMBL6818000 | 0.67 | PPARA (0.60) | PPARAPPARGPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084102-B1 | NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
| EP-1084102-A1 | NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS | AstraZeneca AB (SE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062871-A1 | NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS | ASTRAZENECA AB (SE) | 1999-12-09 | — | — | WO | disclosed |