Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208044 | 0.85 | ALDH1A1 (0.44) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL7987761 | 0.85 | ALDH1A1 (0.55) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL5993835 | 0.85 | HPGD (0.51) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL5698676 | 0.80 | PPARA (0.48) | PPARAPPARGALDH1A1S1PR1LTA4H | |
| SCHEMBL5994194 | 0.76 | PPARA (0.50) | PPARAPPARGS1PR1STSS1PR3 | |
| SCHEMBL8389838 | 0.76 | ALDH1A1 (0.54) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL7996977 | 0.75 | ALDH1A1 (0.46) | PPARAPPARGALDH1A1LMNAMAPT | |
| SCHEMBL10625111 | 0.75 | ALDH1A1 (0.53) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8386827 | 0.75 | ALDH1A1 (0.53) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL31497792 | 0.74 | MMP2 (0.41) | PPARAPPARGALDH1A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084103-B1 | NEW 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVE (I) | ASTRAZENECA AB (SE) | 2003-08-06 | — | — | EP | disclosed |