Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208039 | 0.85 | PPARA (0.45) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL7987761 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL5993835 | 0.72 | HPGD (0.51) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL7996910 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL7996977 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL7987746 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL465539 | 0.71 | HPGD (0.69) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL7987738 | 0.71 | MEN1 (0.55) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL13156122 | 0.71 | PPARA (0.57) | PPARAPPARGPPARDCA12CA1 | |
| SCHEMBL12442802 | 0.71 | PPARA (0.57) | PPARAPPARGPPARDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084103-B1 | NEW 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVE (I) | ASTRAZENECA AB (SE) | 2003-08-06 | — | — | EP | disclosed |