Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 10/20 | 0.74 |
| ▸ | PLAU | P00749 | 9/20 | 0.74 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363270 | 0.88 | TDP1 (0.78) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL7363271 | 0.88 | TDP1 (0.78) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL7418027 | 0.79 | ITGB3 (0.62) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL7418020 | 0.79 | ITGB3 (0.62) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL3458998 | 0.78 | MMP9 (0.76) | ITGB3ITGA2BTDP1MMP9 | |
| SCHEMBL21538609 | 0.78 | MMP9 (0.76) | ITGB3ITGA2BTDP1MMP9 | |
| SCHEMBL1509767 | 0.77 | ITGB3 (0.71) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL9293208 | 0.77 | ITGB3 (0.71) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL1509766 | 0.77 | ITGB3 (0.71) | HPNPLAUITGB3ITGA2BTDP1 | |
| SCHEMBL7752365 | 0.76 | ITGB3 (0.62) | HPNPLAUITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613324-B1 | Comprising: fibrinogen; batroxobin; fibronectin; reducing agent; calcium chloride; and activated blood coagulation factor XIII; permitting batroxobin to split fibrinopeptide A, from said fibrinogen, thereby gluing tissue | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-02 | — | — | US | claimed |