Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | HPN | P05981 | 7/20 | 0.61 |
| ▸ | PLAU | P00749 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363270 | 1.00 | TDP1 (0.78) | TDP1ITGB3ITGA2BMMP9HPN | |
| SCHEMBL7208206 | 0.88 | HPN (0.74) | TDP1ITGB3ITGA2BMMP9HPN | |
| SCHEMBL11648132 | 0.86 | MMP9 (0.68) | TDP1ITGB3ITGA2BMMP9HPN | |
| SCHEMBL6252463 | 0.84 | TDP1 (0.79) | TDP1ITGB3ITGA2BMMP9L3MBTL1 | |
| SCHEMBL4522161 | 0.84 | TDP1 (0.79) | TDP1ITGB3ITGA2BMMP9L3MBTL1 | |
| SCHEMBL697476 | 0.83 | MMP2 (0.79) | TDP1MMP9MMP2 | |
| SCHEMBL697477 | 0.83 | MMP2 (0.79) | TDP1MMP9MMP2 | |
| SCHEMBL1203540 | 0.83 | MMP2 (0.79) | TDP1MMP9MMP2 | |
| SCHEMBL8063645 | 0.83 | TDP1 (0.78) | TDP1MMP9L3MBTL1MEN1KMT2A | |
| SCHEMBL8650150 | 0.83 | TDP1 (0.77) | TDP1MMP9L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265668-A | Substituted phenylalanine-type compounds that inhibit VLA-4 mediated leukocyte adhesion | ELAND PHARMACEUTICALS CO (US) | 2000-09-06 | — | — | CN | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |