Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654659 | 0.84 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL8654656 | 0.84 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL10604052 | 0.69 | KCNH2 (0.64) | KCNH2KMT2AMEN1MAPTADRA2A | |
| SCHEMBL272970 | 0.69 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL29397508 | 0.69 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL272969 | 0.69 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL29397420 | 0.69 | KCNH2 (0.47) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL8206882 | 0.68 | KCNH2 (0.46) | KCNH2KMT2AMEN1LMNAMAPT | |
| Bromide SCHEMBL30705401 | 0.68 | KCNH2 (0.48) | KCNH2KMT2AMEN1LMNAMAPT | |
| SCHEMBL7913558 | 0.68 | ADRA2A (0.59) | KMT2AMEN1LMNAMAPTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946941-B1 | COMPLEX POLYMETHINE DYES AND THEIR USE | CIBA SC HOLDING AG (CH) | 2003-10-15 | — | — | EP | disclosed |
| EP-0946941-A1 | COMPLEX POLYMETHINE DYES AND THEIR USE | Ciba SC Holding AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028737-A1 | COMPLEX POLYMETHINE DYES AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-07-02 | — | — | WO | disclosed |