Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037669 | 0.96 | NAAA (0.43) | NPC1NAAAALDH1A1KMT2ALMNA | |
| SCHEMBL7278778 | 0.94 | NAAA (0.45) | NPC1NAAA | |
| SCHEMBL1949591 | 0.89 | LMNA (0.41) | NPC1NAAALMNAMAPTPKM | |
| SCHEMBL1280223 | 0.88 | LMNA (0.40) | NPC1NAAALMNAMAPTPKM | |
| SCHEMBL16049982 | 0.84 | ALDH1A1 (0.39) | NPC1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL1727857 | 0.81 | GLA (0.32) | NPC1 | |
| SCHEMBL9204462 | 0.80 | NAAA (0.41) | NPC1NAAAALDH1A1 | |
| SCHEMBL5816927 | 0.80 | POLB (0.35) | NPC1CRBNDDB1POLB | |
| SCHEMBL10630839 | 0.79 | NAAA (0.40) | NPC1NAAAALDH1A1 | |
| SCHEMBL3151670 | 0.78 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272500-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001040163-A1 | A PROCESS FOR PRODUCING AMINE COMPOUND WITH t-BUTOXYCARBONYL GROUP | KOREA FINE CHEMICAL CO.,LTD. (KR) | 2001-06-07 | — | — | WO | disclosed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | disclosed |