Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7208818

C1=CC([Zr+2](C2C=Cc3ccccc32)=[Si](Cc2ccccc2)Cc2ccccc2)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.30
CHRM1 known ✓ P11229 1/20 0.30
CHRM3 known ✓ P20309 1/20 0.30
SLC6A2 known ✓ P23975 1/20 0.30
SLC6A3 known ✓ Q01959 1/20 0.30
SIGMAR1 Q99720 6/20 0.36
HTR2A P28223 2/20 0.36
HTR6 P50406 1/20 0.36
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7643741 0.81 HTR2A (0.38) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL7639448 0.78 HTR2A (0.36) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL614845 0.76 HTR2A (0.35) SIGMAR1HTR2AHTR6
Hydrochloric Acid SCHEMBL30661223 0.76 HTR2A (0.35) SIGMAR1HTR2AHTR6
Hydrochloric Acid SCHEMBL7722059 0.76 SIGMAR1 (0.32) SIGMAR1
Hydrochloric Acid SCHEMBL376489 0.75 HTR2A (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL966189 0.75 HTR2A (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL29407230 0.75 HTR2A (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL7766818 0.73 HTR2A (0.36) SIGMAR1HTR2AHTR6KDM4ELMNA
Hydrochloric Acid SCHEMBL7642380 0.73 HTR2A (0.37) SIGMAR1HTR2AHTR6KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891382-B1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LTD (JP) 2003-05-28 EP disclosed
US-6476153-B2 INCLUDES A STEP OF DISTILLING UNREACTED DICYCLOPENTADIENE OR HYDROGENATED PRODUCT THEREOF, TETRAHYDRODICYCLOPENTADIENE FROM A MIXTURE OF THE COPOLYMER OR ITS HYDROGENATED PRODUCT IN THE PRESENCE OF A HIGH BOILING HYDROCARBON SOLVENT TEIJIN LIMITED (JP) 2002-11-05 US disclosed
US-6388032-B1 SEPARATION BY FILTRATION TEIJIN LIMITED (JP) 2002-05-14 US disclosed
US-20010009950-A1 Process for producing hydrogenated alpha-olefin- dicyclopentadiene copolymer, method for molding the same and optical material HASHIDZUME KIYONARI (JP) 2001-07-26 US disclosed
US-6232407-B1 MELT PROCESSABILITY TEIJIN LIMITED (JP) 2001-05-15 US disclosed
US-6191243-B1 ADDITION COPOLYMER HAVING HIGH DEGREE OF ALTERNATING ACYCLIC OLEFIN-DICYCLOPENTADIENE UNITS; OPTICAL RECORDING MEDIA SUBSTRATES TEIJIN LIMITED (JP) 2001-02-20 US disclosed
EP-1028128-A1 CYCLOOLEFIN POLYMER REDUCED IN CATALYST RESIDUE CONTENT, USE THEREOF, AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2000-08-16 EP disclosed
EP-0964005-A1 Process for producing hydrogenated alpha-olefin-dicyclopentadiene copolymer, method for molding the same and optical material TEIJIN LIMITED (JP) 1999-12-15 EP disclosed
EP-0891382-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1999-01-20 EP disclosed
WO-1998033830-A1 ALPHA-OLEFIN-CYCLOOLEFIN COPOLYMERS AND PROCESS FOR THEIR PRODUCTION TEIJIN LIMITED (JP) 1998-08-06 WO disclosed