Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366672 | 0.83 | KDM4E (0.53) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL546185 | 0.82 | RAB9A (0.68) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7212405 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9446981 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9052059 | 0.80 | RAB9A (0.66) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6026021 | 0.80 | MEN1 (0.49) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL31592021 | 0.79 | MAP4K4 (0.47) | KMT2ARAB9ANPC1MAPTMAP4K4 | |
| SCHEMBL4386263 | 0.79 | KDM4E (0.72) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2094743 | 0.79 | MMP2 (0.45) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2094739 | 0.79 | MAP4K4 (0.41) | KDM4EMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077984-B1 | 2\"-DEOXY HYGROMYCIN DERIVATIVES | PFIZER PROD INC (US) | 2003-06-18 | — | — | EP | claimed |
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |