Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | CCR1 | P32246 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446986 | 0.87 | KDM4E (0.63) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL546185 | 0.86 | RAB9A (0.68) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9052059 | 0.85 | RAB9A (0.66) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27496748 | 0.84 | KDM4E (0.59) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| Tetraethylene Glycol SCHEMBL6031544 | 0.83 | KDM4E (0.57) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL18594026 | 0.83 | KDM4E (0.58) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL170428 | 0.83 | MEN1 (0.68) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL5654520 | 0.83 | KDM4E (0.58) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL21753772 | 0.83 | KDM4E (0.58) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL3860121 | 0.83 | KDM4E (0.58) | KDM4ELMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227626-A1 | NOVEL POLYQUINOLINE DERIVATIVES AND THERAPEUTIC USE THEREOF | PALUMED S.A. (FR) | 2009-09-10 | — | — | US | claimed |
| US-20240201165-A1 | NANOPORE-BASED ANALYSIS OF ANALYTES | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2024-06-20 | — | — | US | disclosed |
| WO-2024117910-A1 | NANOBODY-FUNCTIONALIZED BIOLOGICAL NANOPORES AND MEANS AND METHODS RELATED THERETO | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024091124-A1 | NANOPORE-BASED ANALYSIS OF PROTEINS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2024-05-02 | — | — | WO | disclosed |
| EP-1919894-B1 | NOVEL POLYQUINOLINE DERIVATIVES AND THE THERAPEUTIC USE THEREOF | PALUMED SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8324196-B2 | Polyquinoline derivatives and the therapeutic use thereof | PALUMED S.A. (FR) | 2012-12-04 | — | — | US | disclosed |
| US-20120277265-A1 | NOVEL POLYQUINOLINE DERIVATIVES AND THE THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2012-11-01 | — | — | US | disclosed |
| US-8247396-B2 | Polyquinoline derivatives and therapeutic use thereof | PALUMED S.A. (FR) | 2012-08-21 | — | — | US | disclosed |
| US-20090227626-A1 | NOVEL POLYQUINOLINE DERIVATIVES AND THERAPEUTIC USE THEREOF | PALUMED S.A. (FR) | 2009-09-10 | — | — | US | disclosed |
| CN-100514706-C | Gravure plate, method for forming light-emitting layer or hole-injection layer using the same, and organic light-emitting device | DAINIPPON PRINTING CO LTD (JP) | 2009-07-15 | — | — | CN | disclosed |
| US-20060051699-A1 | Radiation-sensitive elements and their storage stability | KODAK POLYCHROME GRAPHICS LLC (US) | 2006-03-09 | — | — | US | disclosed |
| CN-1703437-A | bismuth-catalyzed polyurethane compositions | SIKA TECHNOLOGY AG (CH) | 2005-11-30 | — | — | CN | disclosed |
| US-6479669-B2 | PEPTIDE MIMETICS | PHARM-ECO LABORATORIES, INC. | 2002-11-12 | — | — | US | disclosed |
| CN-1353103-A | Functional dendritic molecular material and its preparing process | UNIV FUDAN (CN) | 2002-06-12 | — | — | CN | disclosed |
| US-20020010342-A1 | AMINO ACID DERIVATIVES AND METHODS OF MAKING THE SAME | JOHNSON MATTHEY PHARMACEUTICAL MATERIALS, INC. | 2002-01-24 | — | — | US | disclosed |
| EP-0725563-A1 | MARINE STRUCTURE | J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011592-A1 | MARINE STRUCTURE | J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) | 1995-05-04 | — | — | WO | disclosed |
| EP-0387499-B1 | Substituted oxine ethers and their use as pesticides | BAYER AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0387499-A3 | SUBSTITUTED OXINE ETHERS AND THEIR USE AS PESTICIDES | — | 1990-11-22 | — | — | EP | disclosed |
| EP-0387499-A2 | Substituted oxine ethers and their use as pesticides | BAYER AG (DE) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277265-A1 | NOVEL POLYQUINOLINE DERIVATIVES AND THE THERAPEUTIC USE THEREOF | HTT, APP, PSEN1 | KDM4E 4293/4885LMNA 1091/4885MAPT 14/4885 |
| US-20020010342-A1 | AMINO ACID DERIVATIVES AND METHODS OF MAKING THE SAME | DAO, PRMT8, PRMT5 | KDM4E 865/4885LMNA 2105/4885MAPT 4376/4885 |
| US-20090227626-A1 | NOVEL POLYQUINOLINE DERIVATIVES AND THERAPEUTIC USE THEREOF | HTT, UBQLN2, UBQLN1 | KDM4E 3878/4885LMNA 625/4885MAPT 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.