Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | M6PR | P20645 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237848 | 1.00 | M6PR (0.42) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL3235088 | 1.00 | M6PR (0.42) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL3235093 | 1.00 | M6PR (0.42) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL10231826 | 1.00 | M6PR (0.42) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL24605082 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL15121661 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL2233716 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL15273797 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL1832193 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 | |
| SCHEMBL2505909 | 0.97 | M6PR (0.44) | M6PRMGAMSIG6PDFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |
| US-6204249-B1 | L-benzimidazole nucleosides | GLAXO WELLCOME INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0876389-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025337-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1997-07-17 | — | — | WO | disclosed |